The introduction of novel pathogens to naïve host populations has caused catastrophic impacts and species extinctions. However, the mechanisms allowing hosts to persist with these same pathogens in disease-endemic (native) regions are poorly known, despite the strong potential for this information to provide insight into host-pathogen coexistence. White-nose syndrome, a devastating disease of North American hibernating bats, was recently introduced to North America from Eurasia, and genetic evidence suggests it has been present for millennia. My research examines the global dynamics of white-nose syndrome (WNS) on bats and in the environment to determine how species and populations in endemic regions persist with this disease.
Selected publications:
Hoyt, J.R., Langwig K.E., Sun K., Parise K.L., Wang Y., Huang X., Worledge L., Miller H., Görföl T., Boldogh S.A., Fukui D., Sakuyama M., Yachimori S., Sato A., Dalannast M., Jargalsaikhan A., Batbayar N., Yovel Y., Amichai E., Natradze I., Frick W.F., Foster J.T., Feng J. and Kilpatrick A.M. 2020. Environmental reservoir dynamics predict global infection patterns and population impacts for the fungal disease white-nose syndrome. Proceedings of the National Academy of Sciences. 117(13)
Hoyt, J.R.*, K.E. Langwig*, K. Sun, G. Lu, K.L. Parise, T. Jiang, S. Yang, W.F. Frick, J.T. Foster, J. Feng, A.M. Kilpatrick. 2016. Host persistence or extinction from emerging infectious disease: insights from white-nose syndrome in endemic and invading regions. Proceedings of the Royal Society B. 283: 20152861
Hoyt J.R., Sun K., Parise K.L., Lu G., Langwig K.E., Jiang T., Frick W.F., Kilpatrick A.M., Foster J.T., Feng J. 2016 Widespread Bat white-nose syndrome fungus in northeastern China. Emerging Infectious Diseases. 22(1) 140-2 Open Access Link
Drees K. P., J. M. Lorch, S. J. Puechmaille, K.L. Parise, G. Wibbelt, J. R. Hoyt, K. Sun, A. Jargalsaikhang, M. Dalannast, J. Palmer, D. L. Lindner, A. M. Kilpatrick, T. Pearson, P. S. Keim, D. S. Blehert, J. T. Foster. 2017. Phylogenetics of a fungal invasion: Origins and widespread dispersal of white-nose syndrome. mBio. 8:e01941-17.
Frick, W.F., Puechmaille S.J., Hoyt J.R., Nickel B.A., Langwig K.E., Foster J.T., Barlow K.E., Bartonička T., Feller D., Haarsma A.J., Herzog C., Horáček I., van der Kooij J., Mulkens B., Petrov B., Reynolds R., Rodrigues L., Stihler C.W., Turner G.G., Kilpatrick A.M. 2015. Disease alters macroecological patterns of North American bats. Global Ecology and Biogeography. DOI: 10.1111/geb.12290